None of the patients showed multiple pituitary hormone deficiencies.
Nineteen healthy children matched for age and sex acted as controls.
Patients with GHD showed a significant increase in TT (3) at twelve months and in FT (3) at six and twelve months after starting GH treatment, with a significant decrease at eighteen and twenty-four months.
TT (4) level decreased significantly at twelve months and increased significantly at eighteen and twenty-four months.
Staphylococcus aureus was the causative organism most commonly detected in the hospital-acquired cases.
Antimicrobial therapy was effective in all cases; surgery was not required.
We report a case of a 14-year-old girl with severe IM and acute abdominal pain.
The SDS of Growth Velocity (SDS-GV) increased remarkably during the first year of therapy and then decreased significantly during the second year, although it remained significantly higher than the pre-therapy values.
Growth hormone (GH) treatment in patients with GH deficiency (GHD) can determine changes in the thyroid function.
The clinical significance of these changes remains controversial, and all studies have so far covered rather a short period--usually no longer than one year.
CT scan showed multiple enlarged lung nodules of various sizes and a small pleural and pericardial effusion; a hypodense solid mass of unknown etiology was detected in the anterior mediastinum, mimicking a malignant tumor.
Hematological analysis of peripheral blood smear was performed to exclude neoplastic pathology. The patient was carefully monitored: clinical evaluation, laboratory analysis and US examination were repeated at weekly intervals, until recovery.