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Domesticated dogs are clearly distinguishable from wolves by starch gel electrophoresis of red blood cell acid phosphatase.

For example, height measured to the withers ranges from a 6 inches (150 mm) in the chihuahua to 3.3 feet (1.0 m) in the Irish wolfhound; color varies from white through grays (usually called "blue") to black, and browns from light (tan) to dark ("red" or "chocolate") in a wide variation of patterns; coats can be short or long, coarse-haired to wool-like, straight, curly, or smooth.

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They perform many roles for humans, such as hunting, herding, pulling loads, protection, assisting police and military, companionship and, more recently, aiding disabled people and therapeutic roles.

A number of common human foods and household ingestibles are toxic to dogs, including chocolate solids (theobromine poisoning), onion and garlic (thiosulphate, sulfoxide or disulfide poisoning), The nicotine in tobacco can also be dangerous.

Dogs can be exposed to the substance by scavenging through garbage bins or ashtrays and eating cigars and cigarettes.

Wozencraft referred to the m DNA study as one of the guides in forming his decision.

Dogs are predators and scavengers, and like many other predatory mammals, the dog has powerful muscles, fused wrist bones, a cardiovascular system that supports both sprinting and endurance, and teeth for catching and tearing. The smallest known adult dog was a Yorkshire Terrier, that stood only 6.3 cm (2.5 in) at the shoulder, 9.5 cm (3.7 in) in length along the head-and-body, and weighed only 113 grams (4.0 oz).

The largest known dog was an English Mastiff which weighed 155.6 kg (343 lb) and was 250 cm (98 in) from the snout to the tail.

Dogs are susceptible to theobromine poisoning, typically from ingestion of chocolate.

Theobromine is toxic to dogs because, although the dog's metabolism is capable of breaking down the chemical, the process is so slow that for some dogs even small amounts of chocolate can be fatal, especially dark chocolate.

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